I saw you were looking about patterns.
Here's what I've discovered:
Ticket #'s ending in 5 seem to do slightly better than other tickets. Some people also swear that #000 and the last of the roll is good, but for me that's been hit/miss.
Scratching a losing ticket with the code "N E W" usually signals a dead roll or a large consecutive number of losers, usually broken up only by a break-even ticket value winner
14,17,18,34,38 Seem to be a series of good winning numbers. Usually when i encounter at least 4 of these numbers in the "Your Numbers" section, its usually a winner
I have seen as many as 27 of 28 consecutive tickets as losers. If you go back to 1 of my first posts at this site I ran an experiment where I purchased #039-#299 of a $1 Holiday Cash game, looking for patterns. Ticket #128 was a $40 winner, but 13 or so before that and the 12 or so after that were losers.
On 100X I once scratched #27-34, all losers, which is like 3 times the odds. If I remember what some others have posted, some have gone through GRT rolls where the first half of the roll was all losers.
I really wish FL would be more open about the odds/prizes like some of the other states are, posting the actual number of all prizes available and in play. I find it misleading when they say a game has 1 of 5 Top prizes remaining and 7 of 54 Second Place prizes remaining, then say all the tickets to distribute are out in the marketplace when knowing the buying pattern something should have been claimed by now. If they're not putting these winners out, then the odds should be stated as 0, not 1 in whatever. It has nothing to do with prior sale or "normal business". If those top amounts aren't going to be released then the odds should be adjusted to reflect 0. There's too many bulk buyers on this site (and FL in general) that tell me something is not right here.